Friday, February 26, 2010
Weekly Assignment 1
Monday, February 8, 2010
MDMA (Ecstasy)
The drug MDMA is a potent indirect monoaminergic agonist.
What it does to the brain:
MDMA exerts its primary effects in the brain on neurons that use the chemical serotonin to communicate with other neurons. The serotonin system plays an important role in regulating mood, aggression, sexual activity, sleep, and sensitivity to pain. MDMA also causes excessive release of serotonin from its neurons. MDMA can produce confusion, depression, sleep problems, drug craving, and severe anxiety. These problems can occur soon after taking the drug or, sometimes, even days or weeks after. In addition, chronic users of MDMA perform more poorly than nonusers on certain types of cognitive or memory tasks. Research in animals indicates that MDMA can be harmful to the brain.
What are the long term effects?
MDMA produces feelings of increased energy euphoria, emotional warmth, and distortions in time perception and tactile experiences.
What happens if MDMA is abused?
MDMA can be dangerous to everybody's overall health and it can even be lethal. MDMA can have many of the same effects as other stimulants (increase in heart rate and blood pressure) such as cocaine and amphetamines; other symptoms include muscle tension, involuntary teeth clenching, nausea, blurred vision, faintness, and chills or sweating. In high doses, MDMA can interfere with the body’s ability to regulate temperature. On rare but unpredictable occasions, this can lead to a huge increase in body temperature which can result in liver, kidney, and cardiovascular system failure, and even death.